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Important caveat: injectable and IV NAD+ are not FDA-approved (nor approved by any major regulator) for energy, metabolic or longevity uses, and their safety and efficacy for these marketed uses are not established

The combination hasn't been studied in controlled human clinical trials

Conditions such as pernicious anemia, which affects the absorption of B12, may also warrant coverage, as well as certain chemotherapy treatments that necessitate B12 supplementation

These molecules are key players in the feedback loops that keep systems in homeostasis

Unnecessary supplementation may mask other underlying causes of fatigue or health concerns