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J Biol Chem 279: 3987239879 Credle JJ, FinerMoore JS, Papa FR, Stroud RM, Walter P (2005) Inaugural article: on the mechanism of sensing unfolded protein in the endoplasmic reticulum

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Its Phase 3 weight-loss figures (in the low-to-mid 20% range) and its late-2025 FDA filing belong to the combination product, not to standalone cagrilintide, which remains at the Phase 2 stage with a peer-reviewed monotherapy result of about 10.8% at 26 weeks