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Obesity-associated adipose tissue thus functions as an inflammatory endocrine organ, particularly in visceral tissue producing TNF-, IL-6, IL-1, Monocyte chemoattractant Protein 1 (MCP-1, which is associated with tamoxifen resistance), and leptin while reducing adiponectin (an anti-inflammatory adipokine) levels, thereby promoting chronic low-grade inflammation, insulin resistance, and tumor-promoting signaling pathways

Physicians may also express concern about medication access after initial success, particularly if insurance coverage lapses

Use in connection with the development, testing, or production of controlled or illegal substances

doi: 10.3329/bjmb.v4i2.13772 24 AlahmarATSenguptaP

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