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These patients were randomized in a 1:1 ratio to finerenone or placebo and subsequently followed for up to 42 months for a primary composite endpoint of cardiovascular death and total heart failure events, which investigators defined as hospitalizations for heart failure or urgent heart failure visits

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Glucagon-like peptide 1 (GLP-1) is an incretin 30 amino-acid peptide hormone produced in hindbrain neurons and in specialized enteroendocrine cells (L cells) in the distal small and large intestines that is released after food intake [23, 24]