This dual mechanism (direct scavenging plus activation of endogenous defenses) addresses limitations of conventional antioxidants that work through single pathways
The most frequently reported side effects include: Nausea (affecting approximately 1040% of patients, depending on the specific medication) Vomiting Diarrhoea Constipation Abdominal discomfort or bloating Reduced appetite These effects typically occur because GLP-1 medications slow gastric emptying and affect gut motility
Because theyre generic, they have a lower out-of-pocket cost than the brand-name versions
It is important to note that weight changes during menopause are multifactorial, influenced by hormonal shifts, ageing-related metabolic changes, and lifestyle factors
Biochem Biophys Res Commun 298:779784 Mulherin AJ, Oh AH, Kim H, Grieco A, Lauffer LM, Brubaker PL (2011) Mechanisms underlying metformin-induced secretion of glucagon-like peptide-1 from the intestinal L cell