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David Barker in the 1990s following the identification of increased incidence of metabolic syndrome in adult children of women who experienced severe malnutrition during the Dutch Potato Famine of 19441945 (Roseboom et al., 2001

doi: 10.1016/j.neuroscience.2012.12.013

We treat it like medicine, which means saying no when the patient isnt ready, monitoring closely when they are, and adjusting protocols based on what bloodwork shows rather than what the patient wants to hear

Khavinson, began investigating the role of short peptides, which he ultimately learned function as epigenetic signals that both promote and repress the expression of whole categories of genes

L-carnitine is not directly associated with overall metabolism