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When keratin buildup occurs, it forms a plug that blocks hair follicles and results in textured, red and bumpy skin associated with keratosis pilaris

Inside cells, the enzyme glutathione reductase (using NADPH as a cofactor) continuously regenerates GSH from GSSG, maintaining a GSH:GSSG ratio of approximately 100:1 under healthy conditions

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This leads to angiogenesisthe formation of new blood vessels

Allicin breaks down in vitro to form a variety of fat-soluble organosulfur compounds ( Figure 2 ), including diallyl trisulfide (DATS), diallyl disulfide (DADS), and diallyl sulfide (DAS), or in the presence of oil or organic solvents, ajoene and vinyldithiins (6)