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One study reported that the percentage of senescent cells in sWAT isolated from older mice (24 months) was almost tenfold that of younger mice (2 months) [33], suggesting that the percentage of senescent sWAT cells is a hallmark of aging [3]

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A synthetic cell-penetrating peptide engineered from a fragment of the FOXO4 protein, also known as Proxofim, FOXO4-DRI is studied as a senolytic that clears worn-out cells