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Weight loss effects increase with higher dosages but side effects are also more likely

This is life changing medication

Haemorrhoidal disease is seen in all age groups from the mid-teens onwards, with incidence tending to increase with age, until the seventh decade of life

The triple-receptor approach is novel no FDA-approved obesity drug currently activates the glucagon receptor which is why long-term safety on retatrutide will need its own evidence base rather than borrowing from the existing GLP-1 class

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