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Similarly, in the CANVAS outcome study, discussed in detail below, LDL cholesterol and HDL cholesterol were also marginally increased in the canagliflozin treated group (LDL cholesterol 4-5 mg/dL and HDL cholesterol 2-3 mg/dL) (144)

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Thus, cystine is the primary amino acid which regulates cellular GSH homeostasis in HepG2 cells

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