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A randomized Phase I study of the safety, tolerability, pharmacokinetics and pharmacodynamics of BI 456906, a dual glucagon receptor/glucagon-like peptide-1 receptor agonist, in healthy Japanese men with overweight/obesity
Examinations of cerebrospinal fluid in individuals with major depressive symptoms have revealed altered concentrations of DSIP compared to healthy controls
By administering the ferroptosis inducers RSL3 and IKE and knocking out the GPX4 gene in immortalized mouse fibroblasts, respectively, Kraft identified a common gene, GCH1, in the surviving cells by genetic sequencing [65]
Then, total RNA (2 g) was reversely transcribed into cDNA using Iscript cDNA Synthesis Kit (Bio-Rad, Milan, Italy), following the manufacturers instructions
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