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This emerging evidence suggests that ethanol-driven lipid peroxidation and impaired antioxidant defence may converge on ferroptotic pathways, thereby linking ER stress, ROS generation and lipid dysmetabolism into a unified neurodegenerative cascade
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Fat (adipose) tissue can release cytokines (cell-signaling molecules) such as tumor necrosis factor-alpha (TNF-) that interfere with the action of insulin (in this context, these cytokines are referred to as adipokines )
