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A persons health history timeline is another important tool in root cause investigation and will help identify ones genetic predisposition (a history of other family members with thyroid or other autoimmune conditions) as well as potential autoimmune triggers (such as infections, heavy metals, periods of stress and the like) that may increase ones chances of having Graves disease

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However, p21 activates Rb to produce a bioactive secretome that places stressed cells under immunosurveillance

The selected articles were chosen based on their relevance to the objective of this review