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Specically, path A is inactive because the energy barrier associated with direct dissociation of the methyl ligand is higher than the barrier of intersection between two dierent electronic states: a metal-to-ligand charge transfer state (MLCT), and a ligand eld state (LF) along the CoO coordinate of the S 1 PES

Yehuda Handelsman: Received research grants, consultant and speaker honoraria from Amgen, AstraZeneca, Bayer, Boehringer Ingelheim, Corcept, Eli Lilly, Ionis, Merck, Novo Nordisk, Regeneron, Sanofi, Verdiva Bio

Androstenedione is an androgen hormone produced from progesterone by the adrenal gland and is a precursor hormone to testosterone

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