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Hippocampal slice preparation Mice were anesthetized and decapitated

GCLC contains 16 exons, encoding for the 637-amino-acids catalytic subunit, whereas GCLM contains 7 exons that encode the 274 amino acids of the modifier subunit

Unregulated IV glutathione may cause life-threatening systemic inflammatory response syndrome (SIRS)

This distinction between preclinical promise and clinical proof is crucial

We think our new work could lead to a clearable nanomedicine that can help detect liver injury much earlier with a simple blood test, and that could help a lot of people. The research was funded by the National Institutes of Healths NIDDK (R01DK103363 and R01DK115986), the Cancer Prevention and Research Institute of Texas, and The Welch Foundation