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GPX1-4 and GPX6 are neutral to selenocysteine, so they can mediate redox reactions by interacting with GSH (Figures 1, 8)

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170 These studies collectively illustrate that a wide range of phytochemicals, including terpenoids (oridonin, triptolide, atractylenolide I), flavonoids (SKN, galangin, engeletin), and phenolics (canolol), act through common and well-conserved inflammatory pathways

Reynolds and colleagues observed that patients with low serum folate levels undergoing treatment with various antidepressant drugs had poorer therapeutic outcomes (30, 65)

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