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If you've had bariatric surgery, semaglutide may interact with your anatomy and require dose adjustment

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Some other incretins, namely, albiglutide and lixisenatide [6, 7], have not been included in hepatic impairment studies because, based on known metabolism pathways, it is expected that these peptide drugs would be broken down into smaller fragments by proteolytic enzymes, and thus there was no expectation for their PK to be influenced by hepatic impairment

doi: 10.1042/BJ20111416

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