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The propensity scores were modeled using a machine learning method called eXtreme Gradient Boosting (XGBoost), which uses a decision tree ensemble approach to optimize the balance of baseline covariates utilized for matching

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The body produces an enzyme called telomerase, which can help maintain or extend telomeres in certain cell types

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Results GSH synthesis is required for the survival of adult animals To better understand the importance of GSH in adult mammals, we developed an inducible, whole-body Gclc KO mouse by breeding the Gclc f/f mouse strain 30 with the Rosa26-CreERT2 mouse strain 31