Because GH and IGF-1 promote protein synthesis and lipolysis, these hormonal changes provide a plausible mechanistic basis for modest increases in lean body mass, improved recovery and support for fat loss seen in clinical and observational contexts, but robust controlled trials explicitly measuring those endpoints are still lacking
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[4] One study which involved murine models with a gene ablation of GHRH (referred to as GHRHKO), commented that the introduction of CJC-1295 might exhibit tissue-specific action
[DOI] [PMC free article] [PubMed] [Google Scholar] 265.Skibicka K.P., Hansson C., Alvarez-Crespo M., Friberg P.A., Dickson S.L
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