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Evidence supports its ability to increase GSH levels, enhance dopamine function, and improve motor and non-motor symptoms

Within this framework, phytonutrients may exert beneficial effects through multiple ways, including antioxidant, anti-inflammatory, microbiota-modulating and SIRT1-activating properties (see Figure 1)

The reduced precursors NRH and NMNH show promise in overcoming this, although preclinical evidence for health benefits is still limited, and whether their efficacy on functional readouts would be superior to the classic counterparts NR and NMN is also unclear

Consider cycling your use by taking short breaks every 2 to 3 months to maintain effectiveness

Insulin users wanting to reduce doses: GLP-1 medications often allow substantial insulin reduction while improving control