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Glutamate is an amino acid that acts as an excitatory neurotransmitter, binding to its receptor and promoting the activation of neurons

doi:10.3390/cimb45020113

However, in case of the ASCT2, studies showed that cysteine is actually a competitive inhibitor and not a substrate for ASCT2 ( Figure 1 via Multidrug Resistance Protein 1 exporter (MRP1), is cleaved extracellularly by -Glutamyl transferase (GGT) forming -Glutamyl-X substrate and Cysteinyl-Glycine

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The high initial GFP intensity levels observed immediately after DEM exposure could be attributed to a delay of approximately 20 min between the addition of DEM and image acquisition (Fig