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Any discussion of these medications in a weight-loss context refers to off-label use, which must be evaluated and prescribed by a licensed physician

2.9% reported using them for weight loss (i.e., an estimated 1.6 million people), while 1.7% reported using them exclusively for weight loss (equivalent to 910,000 people) i.e., they did not use them for an additional reason such as to lower heart disease risk or regulate blood sugar levels for type 2 diabetes

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Estrogens Theoretically, estrogens might increase the levels and adverse effects of caffeine