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While treatment varies by severity, common approaches include: Dietary Modifications Small, frequent meals Low-fat, low-fiber diet Soft or liquid foods Avoid raw vegetables, fatty meats, and high-fiber grains Medications Prokinetics to improve stomach motility Anti-nausea medications Acid reduction therapies (if needed) Advanced Interventions Feeding tubes (severe cases) IV hydration Gastric electrical stimulation Surgery (rare) Important: Stopping the GLP-1 drug may improve symptoms but many patients continue to experience symptoms long-term

The phase-2 study by Beck et al., 2014 investigated ipamorelin in 114 patients with postoperative ileus at a dose of 0.03 mg/kg intravenously twice daily

Several physicians also reported prescribing GLP-1RAs for additional off-label uses, including chronic inflammatory demyelinating polyradiculoneuropathy (CIDP), and idiopathic intracranial hypertension