This study develops a compound, JMF4073, inhibiting thymidylate (TMP) and cytidylate (CMP) kinases, aiming for a new therapy against TKI-resistant CML
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Research Context This stack pairs two distinct families of growth-hormone-axis research peptides in a single lyophilised vial: CJC-1295 (no-DAC variant, also known as Modified GRF 1-29), a 29-residue tetrasubstituted analogue of the first 29 residues of growth-hormone-releasing hormone (GHRH), and Ipamorelin, a synthetic 5-residue pentapeptide classified as a growth hormone secretagogue (GHS) that acts via the ghrelin receptor (GHS-R1a)
