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In a study analyzing the cessation of Evista in women treated for postmenopausal osteoporosis, bone density markers returned to baseline levels after 120 weeks, with the positive effects on bone turnover lost 6 months post-treatment

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Levothyroxine, which requires consistent absorption for stable thyroid hormone levels, may need dose adjustment or timing modification when used concurrently with this medication

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Consistently, the truncated metabolite GLP-2(333) acts as a partial agonist with great reduction in binding affinity and potency