NF-kB is a master transcription factor that controls the expression of hundreds of genes involved in inflammation, immune activation, and cell survival
Am J Physiology-Lung Cell Mol Physiol 297:L134L142 Badagnani I, Castro RA, Taylor TR, Brett CM, Huang CC, Stryke D, Kawamoto M, Johns SJ, Ferrin TE, Carlson EJ (2006) Interaction of methotrexate with organic-anion transporting polypeptide 1A2 and its genetic variants
Araujo-Lopes, R
and the biological pathways in which differential genes were involved included apoptotic process involved in development, extracellular structure organization, activation of MAPKK activity, apoptotic process involved in morphogenesis, positive regulation of coagulation, positive regulation of hemostasis, positive regulation of blood coagulation, regulation of apoptotic process involved in development, cell junction maintenance, and regulation of apoptotic process involved in morphogenesis
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