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Sulfasalazine-mediated GSH depletion inhibits sarcoma cell growth both in vitro and in preclinical mouse models [202]

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Background Glucagon-like peptide-1 receptor agonists (GLP-1RAs), such as exenatide, liraglutide, dulaglutide, and semaglutide, are medications for managing type 2 diabetes (T2D) [1], [2], [3], [4]

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This provides evidence towards potentially using ASOs to inhibit NMD of MECP2 , thus opening a therapeutic avenue for the treatment of Rett syndrome