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Other clear candidates include patients with BMI 35+ who have tried and failed multiple structured weight loss approaches, patients with obesity plus severe sleep apnea, and patients with a metabolic syndrome phenotype where reducing insulin resistance matters

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Depending on the product type, testing may include identity confirmation, chromatographic purity by HPLC, net content verification, endotoxins, heavy metals, microbial contamination, residual solvents, and multi-vial conformity testing

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The drugs are popular because, according to the Centers for Disease Control and Prevention (CDC), about 42% of American adults are obese