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Phase 1 is believed to correspond to the high level of activity in the primary afferent as by C-fiber activation due to peripheral stimulation, 9 whereas phase 2 seems to result from the continuous low level of small afferent input, together with a facilitated state of spinal processing

Additionally, multiple sessions over several months are required, making it a time-consuming and costly option for some patients

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The product's success has also been boosted by a lot of public interest in its off-label use for weight loss, which has made it a household name and increased its demand

Stick to unscented, mild soap externally only, avoid douching, and choose breathable cotton underwear to reduce moisture buildup