Biochemically, silica stimulates rice to rapidly produce defense compounds such as phenolics, flavonoids, lignin, callose, and plant toxins, while also increasing the activity of defense enzymes such as peroxidase, phenylalanine ammonia-lyase, polyphenol oxidase, lipoxygenase, and -1,3-glucanase [27]
Among tryptophan metabolites, serotonin (5-HT) is known to aggravate fibrosis by enhancing inflammation, neutrophil infiltration, oxidative stress, and upregulating TGF-1 and type I collagen [113]
NAC Supplement: NAC (N-Acetyl Cysteine) is an amino acid that is proven to be a glutathione precursor, is used by the body to build antioxidants, and supports cellular health
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Some of this is common knowledgeand common sense