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If its advanced, people might pass out or have signs of heart failure

Non-arteritic anterior ischemic optic neuropathy (NAION), affects up to 10 out of 100,000 people in the general population, the researchers, from Harvard Medical School, report in journal JAMA Ophthalmology

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These products interact with amino acids in the skins top layer to produce a temporary brown pigment, which generally lasts for 5 to 7 days and does not require ultraviolet exposure to develop colour

Biochemical and Biophysical Research Communications , 219, 21-25