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Of note, significant transcriptional changes were identified when exposure occurred at 72 hpf, but not 7 dpf, and changes were predominantly induced by the lower BPA concentration

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While the origins of the observed differences between mice and humans with respect to the l-carnitineBBTMATMAO pathway are not clear, the fact that the second reaction in the conversion of l-carnitine into TMA (i.e., BBTMA) showed marked induction with dietary exposure in subjects likely plays a major role in the observed differences

Also READ - Top 5 Apps for Tracking Semaglutide Progress Top GLP-1 gummies for weight loss CRITICAL RULES: Make ONLY the specified edit - do not modify any other text Preserve ALL formatting and line breaks exactly: Keep line breaks in the section content Keep line breaks WITHIN the replacement text If replacement text contains blank lines (line breaks), preserve them exactly Do NOT normalize multi-line text into a single paragraph PRESERVE MARKDOWN LINK SYNTAX: Keep text format for links - do NOT convert to HTML tags DO NOT use HTML entities: Keep & as &, not &, keep " as ", not ", etc