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Y.ChoY.OhE.LeeN.AnH.SungD.et al (2016)

Indeed, it has been described that GLS2-knockout mice develop B-cell lymphomas and hepatocellular carcinomas [207]

The key point is that glutathione plays a central role in neutralising free radicals, supporting immune function, and maintaining healthy skin tone

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A recent study further demonstrated that WBP1-deficient CRC cells regained sensitivity to 5-FU following the restoration of mitochondrial function [65], reinforcing a causal link between mitochondrial homeostasis and drug responsiveness