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Colchicine dose needs to be adjusted in patients with significantly decreased kidney function

*Bao HY, Zhang J, Yeo SJ, et al

Specifically, we observed that R + MSM compared to control was associated with increase in interleukin 1 receptor type 1 (IL1R1), a decrease in toll-like receptor 4 (TLR4), an increase in toll-like receptor 5 (TLR5), a decrease in S100 calcium binding protein A8 (S100A8), and a decrease in S100 calcium binding protein A9 (S100A9) compared to control at various time points after exercise