In animal studies, AOD-9604 treatment reduced body weight gain by over 50% compared to controls over a 19-day period, with increased lipolytic activity in adipose tissue
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Shukla S, Shukla A, Mehboob S, Guha S
10.1089/ars.2011.3904 Summary Keywords nitric oxide, eNOS, endothelium, preclinical evidence, clinical trials Citation Gonzalez M, Clayton S, Wauson E, Christian D and Tran Q-K (2025) Promotion of nitric oxide production: mechanisms, strategies, and possibilities
The copper chelator tetrathiomolybdate, which blocks the copper-dependent catalytic activity of LOX, is presently undergoing a phase II study (NCT00195091) involving patients with breast cancer at moderate to high risk of recurrence