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Following obesity induction, the model mice ( n = 21) were arbitrarily distributed across three intervention arms ( n = 7 per group): semaglutide, tirzepatide, and saline control

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Moreover, supplementation with Lactobacillus plantarum (DP189) and GOS restored gut microbial composition, improved gut and BBB integrity, reduced cortical inflammation and elevated acetylcholinesterase activity, reversing anxiety and depression-like behaviors in mice (Wang J

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Weight loss used to be an uphill battle and was often the main focus of their wellness journey, he explained