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This may be due to the medication directly, or as a result of other side effects like vomiting, which can lead to dehydration

It adds a layer of direct fat mobilization that compounds targeting appetite and metabolism from other angles cannot replicate on their own

However, several challenges need to be addressed to optimize their clinical utility

Seven glucagon-like peptide-1 receptor agonists and polyagonists for weight loss in patients with obesity or overweight: an updated systematic review and network meta-analysis of randomized controlled trials