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Only 26% of patients had been titrated to goal by the primary endpoint at week 30, at which time the mean daily insulin dose was 29 U per day

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Albumin binding also prevents renal filtration of liraglutide, evidenced by the fact that no intact liraglutide could be detected in patients urine in clinical studies [69]

Side effects beyond nausea , including anxiety in some patients, often resolve after the body adjusts to each new dose level