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Thereby, ketamine as the model of schizophrenia in rats [193] (as acute ketamine administration was associated with schizophrenia-like or psychotomimetic symptoms with large effect sizes and an increase in positive and negative symptoms [195,196]) might escape from the extraordinary complexity of extrapolation from animal models of mental disorders in general [197,198,199]
High-quality human pharmacokinetics and long-term safety studies are still needed
Yu X, Hao M, Liu Y, Ma X, Lin W, Xu Q, Zhou H, Shao N, Kuang H
pylori to provide an alternative niche [142]
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