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The substrate-binding site is located in the solvent-exposed cleft between the thumb subdomain and the palm subdomain, which possess a catalytic triad composed of C111, H272 and D286

Involvement of B vitamins in homocysteine metabolism The figure shows the biochemical pathway of B-vitamin and homocysteine metabolism

Vitamin B12 is an essential nutrient that supports red blood cell production, nerve function, and energy conversion

Water Solubility: Because it is highly water-soluble, it is best introduced in the aqueous phase of your formulation at a temperature below 40C to preserve its bioactivity