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Unlike the controls, patients with Wilson disease showed significantly increased plasma levels of T helper (Th) 1 cytokines (IL-2, TNF-, and TNF-), Th2 cytokines (IL-5, IL-10, and IL-13), and Th17 cytokines (IL-23)
However, in some cases, it can be very dangerous and may cause more harm than good
Notably, the antibody accessibility of the S1 subunit (the NTD, subdomain 1 (SD1), subdomain 2 (SD2) and cleavage loop (CL)), were less affected by the glycosylation as was the case for the RBD and CL which were only partially obstructed by glycosylation (Fig
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