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Maa T, Bayley CP, Mrgelin M, Lettmann S, Bonaldo P, Paulsson M, et al

MASLD affects an estimated 25% of the global adult population and is closely linked to hepatic insulin resistance, which in turn drives systemic metabolic dysfunction, elevated triglycerides, impaired glucose regulation, and elevated cardiovascular risk [8]

As a result, IGF-1 LR3 promotes muscle protein synthesis and stops muscle protein breakdown

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Finally, pharmacological targeting of the activity of -glutamyltransferases prevents the breakdown of circulating GSH, reduces tumour cysteine levels and slows tumour growth