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When you take a vitamin by mouth, it breaks down in your digestive tract and stomach, and your body only absorbs around 50% of it

They must survive the harsh, acidic environment of the stomach to reach the intestines, where they can colonize and begin their work

Acid reflux is amplified GLP-1 medications worsen acid reflux because food sits in the stomach longer

10.1111/exd.14167 Exp Dermatol

The compound reaches peak blood levels within 1-3 hours of sublingual administration, which means the strongest appetite control kicks in right around lunchtime, precisely when food decisions tend to get difficult for most people managing their diet on GLP-1 medications