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Administration of Reduced Glutathione in FOLFOX4 Adjuvant Treatment for Colorectal Cancer Effect on Oxaliplatin Pharmacokinetics, Pt-DNA Adduct Formation, and neurotoxicity

fisetin in particular blocks the degradation of IB (the inhibitor of NF-B), which prevents the nuclear translocation of NF-B and the downstream inflammatory cascade (25)

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Tissue Repair Stimulates collagen synthesis and connective tissue regeneration

Reduced GSH (rGSH) is the active form of the tripeptide and the ratio of rGSH: oxidized GSH (GSSH) is normally about 9:1