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All complexes showed unchanged, stable molecule ions during the exposure time, which made them suitable candidates for our plasma exposure experiments

Constipation is severe and unresponsive to multi-modal management

While enteral administration offers several advantages over other routes of drug delivery in terms of convenience, promoting medication compliance, it faces several obstacles, of which the most widely recognized are inefficient absorption owing to physical barriers and an acidic microenvironment, along with degradation by proteases and the first-pass metabolism in the liver

(PubMed) Cooper AJ, Sharp SJ, Luben RN, Khaw KT, Wareham NJ, Forouhi NG