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The molecular mechanism may be via the Keap1/Nrf2/HO-1 axis modulation [10]
[DOI] [PubMed] [Google Scholar] 352.Loh CY, Arya A, Naema AF, Wong WF, Sethi G, Looi CY
Interestingly, some evidence suggests collagen supplementation in the setting of exercise recovery reduces joint pain and improves joint functionality but appears to have no significant effect on post-exercise muscle protein synthesis necessary for hypertrophy and muscle collagen protein synthesis
Patients often experience side effects (for example, persistent cough with ACE inhibitors or muscle pain with high-dose statins), issues with adherence, and even drug resistance or tolerance over time
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