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However, its development is limited by the need for surgery, lack of standardized methods, and lowlevel evidence [50]

To elicit a novel situation, the male mouse and female mouse (in estrous) were placed into a clean cage with ~1.5 cm bedding thickness [26]

The fact that cerebrolysin, which promotes angiogenesis through VEGF upregulation, shows benefit in this specific condition aligns with its known mechanisms