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Discussion Stimulation-secretion coupling in L-cells, and specifically GLUTag cells, is well characterised ( 2+ channels, GPCR pathway activation and cAMP-mediated regulation of exocytosis also play major roles in coupling GLP-1 with the arrival of fatty acids, amino acids and bile in the small intestine ( Little is known about the role of glutamate receptor signaling in gut enteroendocrine cells, but it would appear that, similar to NMDA receptors in pancreatic -cells, NMDA receptor activity also inhibits GLP-1 release from L-cells

X-ray diffraction (XRD) analysis revealed a broad and diffuse diffraction pattern without distinct crystalline peaks corresponding to Zn-based phases, indicating an amorphous structure of the EGCGZn nanocomplex (Fig

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