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In addition, novel regulators such as RNA methylation enzymes (METTL3/14) that modulate GPX4 mRNA stability (176), or RhoA-mediated vascular remodeling that enhances iron leakage into subchondral bone (97), may offer new molecular targets

NAC is currently excluded from the legal definition of a dietary supplement because the FDA approved it as a drug before NAC was marketed as a supplement

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10.1021/ci4000294 34 KomersovA.KomersK.ZdrailovP