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After reconstitution, visible particulates, cloudiness, or an unusual increase in solution viscosity indicate aggregation and loss of monomeric peptide content

185 Besides, other MTHFD2 inhibitors have been reported, including DS18561882 and LY345899 in a substrate-based manner, and treatments based on them decrease cellular NADPH/NADP + ratio, increase cellular ROS levels, and impair tumorigenesis and metastasis

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To view a copy of this license, visit About this article Cite this article Lama, P., Claireaux, H., Flower, L